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Why I volunteered to be infected with dengue fever - NPR
The U.S. has registered over half a million clinical trials since 2000. Here's a look at the business and ethics of human medical experimentation through the eyes of a volunteer.

In aftermath of Eaton and Palisades fires, ER visits surged amid health effects including blood abnormalities, study finds - ABC7 Los Angeles
For the first time, researchers have been able to study the direct health effects the January wildfires had on Angelenos.

Simple Supplement Combo Could Help Fight Deadly Brain Cancer - ScienceAlert
Glioblastoma is a particularly aggressive cancer, but encouraging results from a new study testing two common supplements on glioblastoma tumors could potentially lead to a new way to treat the disease.

Texas Mennonites less likely to vaccinate after outbreak - Boing Boing
Two children died. 762 Texans got sick. West Texas Mennonites emerged from the outbreak less likely to vaccinate than before.

How common is Alzheimer’s? Blood-test study holds surprises - Nature
A survey of Alzheimer’s disease prevalence in Norway confirms earlier estimates and may show how education level relates to risk.

Scientists shed new light on Alzheimer’s warning signs - Financial Times
Researchers find differences according to age and education and reveal men affected as much as women

Restoring youth to old immune cells: mRNA therapy turns back the clock - Nature
Testing in mice suggests that rejuvenating T cells could make vaccines and some cancer therapies more effective.

Prevalence of Alzheimer’s disease pathology in the community - Nature
The prevalence of Alzheimer’s disease neuropathological changes is reported based on blood-based biomarkers in a Norwegian population-based cohort.

Lesion-remote astrocytes govern microglia-mediated white matter repair - Nature
After spinal cord injury, lesion-remote astrocytes acquire heterogeneous, spatially restricted reactivity states that shape neuroinflammation, neural repair and neurological recovery.

Human assembloids recapitulate periportal liver tissue in vitro - Nature
Hepatocyte organoids derived directly from human tissue enable long-term hepatocyte expansion and can be combined with portal mesenchyme and cholangiocyte organoids to form a donor-specific periportal liver assembloid system.

Astrocyte CCN1 stabilizes neural circuits in the adult brain - Nature
Neural circuits in adult mouse visual cortex are stabilized by astrocytes, which secrete CCN1, resulting in reduced plasticity and increased maturation of multiple cell types.

Transient hepatic reconstitution of trophic factors enhances aged immunity - Nature
Using lipid nanoparticle delivery of mRNAs to the liver in aged mice, T cell function and declining immune cues can be restored.

Gene-specific selective sweeps are pervasive across human gut microbiomes - Nature
Development and application of the integrated linkage disequilibrium score (iLDS) reveals both selective pressures impacting the human gut microbiome and the mechanisms by which gut bacteria adapt to meet them.

Researchers Tested Herpes Drugs for Alzheimer’s. It Backfired - Gizmodo
People given the herpes medication valacyclovir actually experienced worse cognitive decline than those given a placebo.

Dairy Doughnut Triggers Dangerous Allergy, United Hatzalah Medics Give Swift Treatment - VINnews
JERUSALEM (VINnews) An unusual medical emergency occurred in Jerusalem during the Hanukkah holiday, when a young man in his early 20s suffered a life-threatening allergic reaction shortly after eating a doughnut. The young man, who has a severe milk allergy, …

He ate a hamburger and died hours later. Doctors found a shocking cause - ScienceDaily
A rare tick-borne allergy linked to red meat has now been confirmed as deadly for the first time. A healthy New Jersey man collapsed and died hours after eating beef, with later testing revealing a severe allergic reaction tied to alpha-gal, a sugar spread by…

There Are Colors Missing From The Sun – And We Still Can't Fully Explain Why - ScienceAlert
One of the best visualizations ever produced of the spectrum of light from our glorious Sun reveals some mysterious holes in its array of colors.

If you're over 65 and can still do these 10 things without help, you're a rare gem of a person - VegOut
While many struggle with basic tasks as they age, there's a select group of seniors who continue conquering challenges that would intimidate people half their age—and the difference isn't just luck or good genes.

Seven feel-good science stories to restore your faith in 2025 - Nature
Immense progress in gene-editing, drug discovery and conservation are just some of the reasons to be cheerful about 2025.

Is bird flu the next pandemic? The science so far - Nature
Key mutations and animal spread could raise the risk to humans.