Generating the integrated IBD scRNA-seq atlas
Previously published scRNA-seq datasets on CD and UC were used for integrative analysis2,9,11,13. The dataset of Smillie et al.2 was generated with colo… [+75712 chars]
Bidirectional CRISPR screens decode a GLIS3-dependent fibrotic cell circuit - Nature
Integrated single-cell and spatial data analysis, combined with bidirectional CRISPR screens, identify the transcription factor GLIS3 as a key driver of chronic inflammation and fibrosis and a potential marker of disease severity in patients with ul…
Source:Nature.com
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