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Neuronal FAM171A2 mediates α-synuclein fibril uptake and drives Parkinson's disease - PubMed

Neuronal accumulation and spread of pathological α-synuclein (α-syn) fibrils are key events in Parkinson's disease (PD) pathophysiology. However, the neuronal mechanisms underlying the uptake of α-syn fibrils remain unclear. In this work, we identified <i>FAM…

Source:National Institutes of Health
Published:
Neuronal FAM171A2 mediates α-synuclein fibril uptake and drives Parkinson's disease - PubMed
Neuronal accumulation and spread of pathological -synuclein (-syn) fibrils are key events in Parkinson's disease (PD) pathophysiology. However, the neuronal mechanisms underlying the uptake of -syn f… [+779 chars]

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