Mice
For LD50 and inhibitor experiments, C57BL/6 female mice from Jackson Laboratories (000664) were used. Young mice were used at 12weeks of age or roughly 12weeks of age (1214weeks). Aged mice wer… [+25905 chars]
Disease tolerance and infection pathogenesis age-related tradeoffs in mice - Nature
Disease course and pathology an infection may cause can change owing to the structural and functional physiological changes that accumulate with age, but therapy can be tailored accordingly; disease tolerance genes show antagonistic pleiotropy.
Source:Nature.com
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