science

Ageing promotes microglial accumulation of slow-degrading synaptic proteins - Nature

Newly developed mouse models that enable cell-specific analyses of proteostasis dynamics across the lifespan of the mice reveal key aspects of neuronal proteostasis with ageing.

Source:Nature.com
Published:
Ageing promotes microglial accumulation of slow-degrading synaptic proteins - Nature
Mouse husbandry Mice were housed in standard conditions on a 12-h lightdark cycle and provided with water and standard chow ad libitum. In some experiments, as documented in the main text, mice were… [+71332 chars]

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